Specification
1. Introduction of Sodium ascorbate
Sodium ascorbate is a more bioavailable[citation needed] form of vitamin C that is an alternative to taking ascorbic acid as a supplement. The IUPAC Name of it is Sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate
2. Properties of Sodium ascorbate
H-Bond Donor: 3
H-Bond Acceptor: 6
Rotatable Bond Count: 2
Tautomer Count: 2
Exact Mass: 198.014033
MonoIsotopic Mass 198.014033
Topological Polar Surface Area: 110
Heavy Atom Count: 13
Complexity: 237
Solubility: H2O: 50 mg/mL
Water Solubility: 620 g/L (20 °C)
Melting Point: 220 °C (dec.)(lit.)
alpha: 104 °(C=1, H2O 25 °C)
Refractive index: 105.5 °(C=10, H2O)
Flash Point: 238.2 °C
Enthalpy of Vaporization: 95.78 kJ/mol
Boiling Point: 552.7 °C at 760 mmHg
Vapour Pressure of Sodium ascorbate: 1.62E-14 mmHg at 25 °C
3. Preparation of Sodium ascorbate
Sodium ascorbate is produced by dissolving ascorbic acid in water and adding an equivalent amount of sodium bicarbonate. After cessation of effervescence, the sodium ascorbate is precipitated by the addition of isopropanol.
4. Use of Sodium ascorbate
As a food additive, it has the E number E301 and is used as an antioxidant and an acidity regulator. Sodium ascorbate can reverse the development of atherosclerotic disease, helps in heart attack prevention. In addition sodium ascorbate plays a significant role in the elimination of chronic and acute infections. Moreover, it is considered to be an anti-cancer agent. Sodium ascorbate produces cytotoxic effect in an array of malignant cell lines, which include melanoma cells that are particularly susceptible.
5. Side-effects of sodium ascorbate
The common side-effects that persist or become troublesome when using sodium ascorbate, especially in a liquid form as injections, include burning, stinging, pain, or swelling at the injection site. Severe allergic reactions include rash; itching; difficult breathing; hives; tightness in the chest; swelling of the mouth, face, lips, or tongue; bone pain; muscle weakness; severe or persistent diarrhea; mental or mood changes.
